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Mesterolone is an oral androgen primarily prescribed to treat sexual dysfunction, lagging libido and/or impotency in men.
To a lesser extent it has also been used in an attempt to increase sperm count in some individuals with varying degrees of success.
It can be run for long periods of time due to the fact that it is not a 17 alpha alkylated compound. This means it is not as toxic since it’s not alkylated in the same fashion, but at the 1 position, which reduces hepatic breakdown.
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There is some evidence that by using this compound when cycling testosterone, it may actually increase it’s potency.
It appears that the Mesterolone will attach to the sex hormone binding globulin (SHBG) and albumin. This leaves a larger percentage of free Testosterone to conduct anabolic actions.
Mesterolone can also be used for it’s action as an anti-aromatase. It is because of this function that many users will use it when stacking other compounds that may partially convert to estrogen.
Mesterolone will bind to the aromatase enzyme. This in turn does not allow other steroids to interact with the enzyme and form estrogen.
Some competitive bodybuilders will also add Mesterolone to their pre-contest preparation as many believe that it will improve muscle density and hardness. This could be attributed to the ability of the compound to decrease water retention and reduce the amount of circulating estrogen in the body. However, there are several other drugs that could be substituted for Mesterolone that are much more effective for this purpose.
Many steroid users who have had adverse reactions to Testosterone, or otherwise do not wish to use Testosterone in their cycle, will often add Mesterolone for it’s ability to increase the libido of a user.
Often when a user does not include Testosterone, or simply not enough Testosterone in relation to the other compounds that he is using, libido will be reduced and including Mesterolone may help alleviate this. Obviously, the Dihydrotestosterone effect of the compound plays a key role in this process.
Use/dosing: The majority of male users will find that dosing in the range of 25 to 100 milligrams per day of Mesterolone will be enough to achieve their desired results.
Females most often remain at about 25 milligrams per day, but many have experimented with levels far higher.
Due to the active life of the compound, splitting the dosage of the drug so that it can be taken twice per day is beneficial, but the effects of the compound should remain for a full twenty four hours so this is not completely necessary.
Due to the fact that many other compounds are available that are much more potent and effective than Mesterolone, it is seemingly unnecessary to increase a user’s dosage far higher than 100mgs per day.
Instead one would most likely be better served to switch compounds and try a much more potent drug if the desired results are not achieved.
Side Effects/risks: Mesterolone is an oral alkylated steroid. If used throughout a longer cycle it may elevate liver values slightly. However, this would be far less than would be expected with a 17-alpha-alkylated steroid. It’s not quite as toxic since its not alkylated in the same way, but at the 1 position, which reduces hepatic breakdown.
This change in the alkylated position would be due to the fact that the 17-alpha position reduces the affinity for sex hormone binding proteins, thereby decreasing the ability of the compound to free testosterone, obviously something that would make the drug far less effective for it’s intended purposes.
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It is because of this that liver toxicity should be of little concern to the user running Mesterolone, even if it is for long periods of time, keeping in mind that other compounds still pose a threat.
The main concern with the compound is the possibility of androgenic side effects. Usually in male users these side effects will only appear if a user is administering large doses of the drug. An individual may encounter the typical side effects of oily skin, acne, exacerbation of male pattern baldness if the condition already exists, and body/facial hair growth.
As should be expected with a compound in which Dihydrotestosterone plays such a major role, prostate problems are not uncommon with users.
Women should also be aware that virilization symptoms are a possibility with use of the compound. Deepening of the voice, menstrual irregulation, and other symptoms could occur.
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Testosterone Cypionate is a slow acting injectable ester of the male androgen Testosterone.
Testosterone is also the main anabolic hormone in men and is the basis of comparison with which all other anabolic/androgenic steroids are judged.
As with all Testosterone injections, Testosterone Cypionate is favorable for athletes for it’s ability to promote strong increases in muscle mass and strength.
It is interesting to note that although a large number of steroidal compounds have been available since Testosterone injectables came out, these are still considered the preferred steroids for the development of muscle mass among bodybuilders.
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American athletes have a long and fond relationship with Testosterone Cypionate.
While Testosterone Enanthate is manufactured widely throughout the world, Cypionate seems to be almost exclusively an American item. It is therefore not surprising that American athletes particularly favour this Testosterone ester. But many claim this is not just a matter of simple pride, often swearing Cypionate to be a superior product, providing a bit more of a “kick” than Enanthate.
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Testosterone is one of the most commonly used substances in an anabolic steroid cycle, it is practically the basis on which most cycles are built.
Within Testosterone we can find different types of substances, each with it’s anabolic properties and characteristic side effects, as with all these types of steroids, the more potent it is the greater and more dangerous its side effects.
One type is Testosterone Propionate, within the scale, Testosterone can be placed at a midpoint, offering an acceptable increase in body muscle mass and energy.
Testosterone does not cause much retention of liquids but has some side effects, these side effects are not of the same intensity or magnitude as those that may appear with Testosterone Enanthate or Testosterone Cypionate.
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Testosterone was the first steroid to be synthesized and now it remains the gold standard of all steroids.
First, we will discuss Testosterone in general and in depth, then we will examine exactly how and what the Propionate ester is (together, Testosterone Propionate is often referred to as just “Prop” Test-p or “Test Prop”).
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