MASTEDRA (Proviron) 25mg 100 tabs (Dragon Pharma)

Mastedra Dragon Pharma

Although this steroid is strongly androgenic, the anabolic effect of it is considered too weak for muscle building purposes. This is due to the fact that Proviron is rapidly reduced to inactive metabolites in muscle tissue, a trait also characteristic of Dihydrotestosterone.

The belief that the weak anabolic nature of this compound indicates a tendency to block the androgen receptor in muscle tissue, thereby reducing the gains of other more potent muscle building steroids.

In fact, due to its extremely high affinity for plasma binding proteins such as SHBG, Proviron may actually work to increase the activity of other steroids by displacing a higher percentage into a free unbound state.

Among athletes Proviron is primarily used as an anti-estrogen. It is believed to act as an anti-aromatase in the body, preventing or slowing the conversion of steroids into estrogen. The result is somewhat comparable to Arimidex (though less profound), the steroid acting to prevent the buildup of estrogen in the body.

This is in direct contrast to Nolvadex, which only blocks the ability of estrogen to bind and activate receptors in certain tissues.

The anti-aromatization effect is preferred, as it is a more direct and efficient means of dealing with the problem of estrogenic side effects.

Mastedra Dragon Pharma

Another disadvantage of Nolvadex is that if discontinued too early a rebound effect may occur as high serum estrogen levels are again free to take action. This of course could mean a rapid onset of side effects such as Gynecomastia. Most actually prefer to use both Proviron and Nolvadex, especially during strongly estrogenic cycles. With each item attacking estrogen at a different angle side effects are often greatly reduced.

The anti-estrogenic properties of Proviron are not unique to this compound. A number of steroids have in fact demonstrated similar activity.

Dihydrotestosterone and Masteron (2Methyl-Dihydrotestosterone) have been successfully used as therapies for Gynecomastia and breast cancer due to their strong anti-estrogenic effect.

It has been suggested that Nandrolone may even lower aromatase activity in peripheral tissues where it is more resistant to estrogen conversion (the most active site of Nandrolone aromatization seems to be the liver).

The anti-estrogenic effect of all of these compounds is presumably caused by their ability to compete with other substrates for binding to the aromatase enzyme.

With the aromatase enzyme bound to the steroid, yet being unable to alter it, and inhibiting effect is achieved as it is temporarily blocked from interacting with other hormones.

This steroid is also favored by many during contest preparations when a lower estrogen/high androgen level is particularly sought after.

This is especially beneficial when anabolics like Winstrol, Oxandrolone and Primobolan are being used alone, as the androgenic content of these drugs is relatively low.

Proviron can supplement a well needed androgen, and bring about an increase in the hardness and density of the muscles.

Women in particular find a single 25mg tablet will efficiently shift the androgen/estrogen ratio and can have a great impact on the physique. Since this is such a strong androgen extreme caution should be taken with administration.

Higher dosages clearly have the potential to cause virilization symptoms. For this reason females will rarely take more than one tablet per day, and limit the length of intake to no longer than four or five weeks.

One tablet used in conjunction with 10 or 20mg of Nolvadex can be even more efficient for muscle hardening, creating an environment where the body is much more inclined to burn off extra body fat (especially in female body trouble areas like the hips and thighs).

The typical dosage for men is one to four 25 mg per tablets per day. This is a sufficient amount to prevent Gynecomastia, the steroid is often used throughout the entire cycle.

It is often combined with Nolvadex (Tamoxifen Citrate) or Clomid (Clomiphene Citrate) when heavily estrogenic steroids are being taken (Dianabol, Testosterone etc.).

Administering 50mg of Proviron and 20mg Nolvadex daily has proven extremely effective in such instances, and it is quite uncommon for higher dosages to be required.

As we discussed for women, the androgenic nature of this compound is greatly welcome during contest preparation. Here again Proviron should noticeably benefit the hardness and density of the muscle, while at the same time increasing the tendency to burn off a greater amount of body fat.

Mastedra Dragon Pharma is usually well tolerated and side effects for men are rare with a dose of under 100 mg per day. Above this, one may develop an excessively high androgen level and encounter some problems.

Typical androgenic side effects include oily skin, acne, body/facial hair growth and exacerbation of male pattern baldness condition, this may occur even with the use of a moderate dose.

With the strong effect DHT has on the reproductive system, androgenic actions may also include an extreme heightening of male libido. Women should be careful around Proviron. It is an androgen, and as such has the potential to produce virilization symptoms quite readily. This includes, of course, a deepening of the voice, menstrual irregularities, changes in skin texture and clitoral enlargement.

Proviron is also not a c17 alpha alkylated compound, an alteration commonly used with oral anabolic/androgenic steroids. Not using this structure in the case of Proviron removes the notable risk of liver toxicity we normally associate with oral drugs. It is therefore considered a “safe” oral steroid, the user having no need to worry about serious complications with use.

This steroid in fact utilizes the same 1-Methylation we see present on Primobolan (Methenolone), another well tolerated orally active compound.

Alkylation at the one position also slows metabolism of the steroid during the first pass, although much less profoundly than 17 alpha alkylation.

Likewise Proviron and Primobolan are resistant enough to breakdown to allow therapeutically beneficial blood levels to be achieved, although the overall bioavailability of these compounds is still much lower than methylated oral steroids.

The popularity of Proviron amongst bodybuilders has been increasing in recent years. Many experienced bodybuilders swear by it, incorporating it effectively in most markedly estrogenic cycles.

Due to high demand Proviron is now very easy to obtain on the black market. Most versions will be manufactured by Schering.

This drug is packaged in both push through strips and small glass vials. There is currently no need to worry about authenticity with this steroid, as no counterfeits are known to exist.

If money and availability does not prevent it, Arimidex, Femara, or Aromasin are actually a much better choice than Proviron. These drugs were designed specifically as an anti-aromatase, and work much more effectively than anything else we have available.

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